20. Guo Q, Lakatos E, Al Bakir I, Curtius K, Graham TA, Mustonen V. (2021) The mutational signatures of formalin fixation on the human genome. bioRxiv doi: 10.1101/2021.03.11.434918 (submitted)

Peer-reviewed articles

19. Curtius K*, Kabir M*, Al Bakir I, Choi CHR, Hartono J, et al. (2021) Multi-centre derivation and validation of a colitis-associated colorectal cancer risk prediction web-tool. Gut (in press) *joint first authors

18. Luebeck GE, Vaughan TL, Curtius K, Hazelton WD. (2021) Modeling historic incidence trends implies early field cancerization in esophageal squamous cell carcinoma. PLoS Comput Biol (in press)

17. Curtius K, Dewanji A, Hazelton WD, Rubenstein JH, Luebeck EG. (2021) Optimal timing for cancer screening and adaptive surveillance using mathematical modeling. Cancer Res 81(4):1123-1134

16. Curtius K, Rubenstein JH, Chak A, Inadomi JM. (2020) Computational modelling suggests that Barrett's oesophagus may be the precursor of all oesophageal adenocarcinomas. Gut, Epub ahead of print doi:10.1136/gutjnl-2020-321598

15. Tamura N, Shaikh N, Muliaditan D, McGuinness J, Moralli D, et al. (2020) Mechanisms of Chromosomal Instability in High-grade Serous Ovarian Carcinoma. Cancer Res 80(20):4946-59

14. Saunderson EA, Baker AM, Williams M, Curtius K, Jones JL, et al. (2020) A novel method of single strand library preparation for whole genome sequencing of formalin-fixed paraffin-embedded tissue samples. NAR Genom and Bioinform 2(1):lqz017

13. Rockne R, Hawkins-Daarud A, Swanson K, Sluka J, Glazier J, et al. (2019) The 2019 Mathematical Oncology Roadmap. Phys Biol doi: 10.1088/1478-3975/ab1a09

12. Baker AM*, Cross WC*, Curtius K*, Al Bakir I*, Choi CHR*, et al. (2019) The evolutionary history of human colitis-associated colorectal cancer. Gut 68:985-995., *joint first authors

11. Luebeck EG, Hazelton WD, Curtius K, Maden S, Yu M, et al. (2019) Implications of Epigenetic Drift in Colorectal Neoplasia. Cancer Res 79(3):495-504

10. Al Bakir I, Curtius K, Graham TA. (2018) From Colitis to Cancer: an Evolutionary Trajectory That Merges Maths and Biology. Front Immunol 9:2368

9. Curtius K, Wright NA, Graham TA. (2018) An evolutionary perspective on field cancerization. Nat Rev Cancer 18: 19-32.

8. Luebeck EG, Curtius K, Hazelton WD, Maden SK, Yu M, et al. (2017) Identification of a key role of widespread epigenetic drift in Barrett’s esophagus and esophageal adenocarcinoma. J Clin Epigenet 9(113): 1-10.

7. Kroep S*, Heberle C*, Curtius K*, Lansdorp-Vogelaar I, Hazelton WD, et al. (2017) Radiofrequency Ablation of Barrett’s Esophagus Reduces Esophageal Adenocarcinoma Incidence and Mortality in a Comparative Modeling Analysis. Clin Gastroenterol Hepatol 15(9):1471-1474, *joint first authors

6. Curtius K, Wong C-J, Hazelton WD, Kaz AM, Chak A, Willis JE, et al. (2016) A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett’s Esophagus. PLoS Comput Biol 12(5): e1004919. 

5. Hazelton WD, Curtius K, Inadomi JM, Vaughn TL, Meza R, et al. (2015) The role of gastroesophageal reflux and other factors during progression to esophageal adenocarcinoma. Cancer Epidemiol Biomarkers Prev: cebp–0323

4. Curtius K, Hazelton WD, Jeon J, Luebeck EG (2015) A Multiscale Model Evaluates Screening for Neoplasia in Barrett’s Esophagus. PLoS Comput Biol 11(5):e1004272. 

3. Kong CY, Kroep S, Curtius K, Hazelton WD, Jeon J, et al. (2014) Exploring the Recent Trend in Esophageal Adenocarcinoma Incidence and Mortality Using Comparative Simulation Modeling. Cancer Epidemiol Biomarkers Prev 23(6):997-1006

2. Luebeck EG, Curtius K, Jeon J, Hazelton WD (2013)  Impact of Tumor Progression on Cancer Incidence Curves. Cancer Res Feb 1;73(3):1086-96

Book chapters

1. Curtius K, Wright NA, Graham TA. (2017) Evolution of Premalignant Disease. Cold Spring Harb Perspect Med. doi: 10.1101/cshperspect.a026542